The COVID-19 pandemic once again shed light on core and age-old challenges facing Latin America. They include governance, public health, economic progress, and social policies, as well as citizen participation in the search for solutions to pressing problems. New technologies which in recent years became accessible to many of the regions poor allowed millions of marginalized Latin Americans to follow how other places around the world were dealing with the health crisis and the political, economic, and social challenges it posed. The authors of the edited volume, both acclaimed and young researchers from the Americas and Europe, address questions about the lessons learned by Latin American countries and societies from the pandemic. The chapters of the edited volume analyze the geopolitical and geoeconomic conditions of the region in the midst of the pandemic, point out key issues which require immediate state intervention, and reflect on the human rights which Latin Americans once again had to fiercely defend, maintaining their hope for a better tomorrow.